Dr. Kaufman is a longtime Spartan, professor and founding chair of the Department of Neurology and Ophthalmology, and Assistant Vice President for Clinical Affairs with the Office of Health Sciences at MSU. He has served as a practicing neuro-ophthalmologist at Michigan State University for over three decades, helping train 70 fellows in neuro-ophthalmology and earning more than 25 MSU teaching awards. During the fall, you can find him on the sidelines as a neurologist for MSU Football.
Throughout his career, Dr. Kaufman’s research and clinical interests have included using the afferent visual system and electrophysiology to assess prognosis and early therapeutic strategies for brain disease such as multiple sclerosis and stroke. He has been cited in “Best Doctors” in neurology multiple times, secured 18 years of sustained NIH funding, and participated on the executive committee of multiple clinical trials.
In addition, Dr. Kaufman has more than 160 peer-reviewed publications, book chapters and abstracts focused on neuro-ophthalmology including several publications on mild traumatic brain injury. More recently he has focused on sports concussion and the development of radiographic biomarkers to assist with prognosis (fMRI scanning).
Dr. Kaufman received his bachelor’s degree from the University of Wisconsin and his medical degree from the Philadelphia College of Osteopathic Medicine. He served as a resident and fellow at the University of Wisconsin. He was a Harvard Clinical Research Fellow while obtaining his neuro-ophthalmology training at Massachusetts General Hospital.
Among many other responsibilities, Dr. Kaufman is helping to strengthen collaboration across the health colleges and MSU Health Care. He is fostering an environment that supports the clinical, education and research goals of every practitioner. He also strives to foster the growth of the academic practice, and be the bringer of health, hope and healing to the people of Michigan.
Academic Appointments
2011-Present: Founding Chair, Sparrow Hospital Department of Neurology, 2000-Present: Professor and Chair, Michigan State University Department of Neurology and Ophthalmology, 2008-2011: Founding Medical Director, Hauenstein Neuroscience Center, Saint Mary's Health Care; Grand Rapids, MI, 1993-2011: Medical Director, Sparrow Hospital Neurosciences; Lansing, MI, 1998-2000: Professor and Director, Michigan State University, Center for Clinical Neuroscience and Ophthalmology, 1996-1998: Professor, Michigan State University, 1988-1996: Associate Professor, Michigan State University, 1984-1988: Assistant Professor, Michigan State Univeristy
Education
- D.O., College of Osteopathic Medicine; Philadelphia, PA 1978
- B.S., Zoology and History, University of Wisconsin; Madison, WI 1973
Postdoctoral Training
Clinical Neuro-Ophthalmology Fellowship, Harvard Research Fellow, Massachusetts General Hospital; Boston, MA 1984, Clinical Neurophysiology Fellowship, University of Wisconsin; Madison, WI 1983, Neurology Residency, University of Wisconsin; Madison, WI 1982, Internship, Cherry Hill Medical Center; Cherry Hill, NJ 1979
Publications
- Kaufman, D., & Friedman, D. (2017). Should Acetazolamide be the First-Line Treatment for Patients with Idiopathic Intracranial Hypertension? Point Counter-Point. Journal of Neuro-Ophthalmology, Vol 37 (pp. 182-186).
- Antonio-Santos A, Murad-Kejbou S, Foroozan R, Yedavally S, Kaufman DI, Eggenberger ER. Preserved Visual Acuity in Anterior Ischemic Optic Neuropathy Secondary to Giant Cell (temporal) Arteritis. Journal of Vascular and Interventional Neurology, 2016 Jan; 8(5): 17-21.
- Bailes J, Bravo S, Breiter H, Kaufman D, Lu Z, Molfese D, Perrish T, Slobounov S, Talavage T, Zhu D. Editorial. A Call to Arms: The Need to Create an Inter-Institutional Concussion Neuroimaging Consortium to Discover Clinically Relevant Diagnostic Biomarkers and Develop Evidence-Based Interventions to Facilitate Recovery. Developmental Neuropsychology, 40(2), 59-62. DOI: 10.1080/87565641.2015.1018090.
- Zhu DC, Covassin T, Nogle S, Doyle S, Russell D, Pearson RL, Monroe J, Liszewski CM, DeMarco JK, Kaufman DI. A potential biomarker in sports-related concussion: brain functional connectivity alteration of the default-mode network measured with longitudinal resting-state fMRI over 30 days. Journal of Neurotrauma. J Neurotrauma. 2015 Mar 1;32(5):327-41. doi: 10.1089/neu.2014.3413. Epub 2014 Dec.
- Alterman MA, Young BK, Eggenberger ER, Kaufman DI. Macular Hole: A Rare Complication of Ocular Bartonellosis. J Neuroophthalmology. 2013 Jun; 33(2): 153-4.
- Young B, Eggenberger E, Kaufman D. Current Electrophysiology in Ophthalmology: A Review. Curr Opinion Ophthalmol. 2012 Nov; 23(6): 497-505.
- Demidenko A, Vakili R, Eggenberger E, Kaufman D. Late onset Leber’s Hereditary Optic Neuropathy. NOPH Neuro-Ophthalmology Volume 32:1, February 2008.
- Hong H, Zeng J, Kreulen D, Kaufman D, Chen A. Atorvastatin protects against cerebral infarction via inhibition of NADPH oxidase-derived superoxide in ischemic stroke. Am J Physiol Heart Circ Physiol, 2006:291:2210-2215.
- Warach S, Kaufman D, Chiu D, Devlin T, Luby M, Rashid A, Clayton L, Kaste M, Lees KR, Sacco R, Fisher M. The effect of the glycine antagonist gavestinel on cerebral infarcts in acute stroke patients, a randomized-placebo controlled trial: The GAIN MRI substudy. Cerebrovascular Diseases, 2006:21:106-111.
- Smolyar A, Eggenberger ER, Kaufman DI. Monocular Temporal Hemianopia Associated with Optic Nerve Hypoplasia. Arch Ophthalmology. 2005:123; 1155.
- Kidd G, Hong H, Majid A, Kaufman DI, Chen AF. Inhibition of Brain GTP Cyclohydrolase I and Tetrahydrobiopterin Attenuates Cerebral Infarction via Reducing Inducible NO Synthase and Peroxynitrite in Ischemic Stroke. Stroke, 2005:36:2705-2711.
- Huang J, Cooper TG, Satana B, Kaufman DI, Cao, Y. Visual Distortion Provoked by a Stimulus in Migraine Associated with Hyperneuronal Activity. Headache. 2003;43:664-671.
- Kaufman DI, Dickersin K, Newman N, Kelman S, et al. and the IONDT Research Group. Ischemic Optic Neuropathy Decompression Trial: Twenty-Four Month Update. Arch Ophthalmol, 2000; 118:793-798.
- Eggenberger ER, Kaufman DI. Ocular Motility Review for 1997-1998: Part II. Journal of Neuro- Ophthalmology, 20(3): 192-206, 2000.
- Eggenberger ER, Kaufman DI. Ocular Motility Review for 1997-1998: Part I. Journal of Neuro-Ophthalmology 20(2): 73-84, 2000.
- Kaufman DI, Fratkin J. Clinical Challenges - Really Painful Double Vision (comments). Survey of Ophthalmology 45(2): 155-9, 2000.
- Eggenberger ER, Desai NP, Kaufman DI, Pless M. Internuclear Ophthalmoplegia After Coronary Artery Catheterization and Percutaneous Transluminal Coronary Balloon Angioplasty. Journal of Neuro-Ophthalmology 20(2): 123-126, 2000.
- Kaufman DI, Trobe JD, Eggenberger ER, Whitaker JN. Practice Parameter: The Role of Corticosteroids in the Management of Acute Monosymptomatic Optic Neuritis. Neurology, 2000; 54(11):2039-2044.
- Vaphiades3 M, Kaufman DI, Eggenberger ER. Visual Recovery in Treated Giant Cell Arteritis. Ophthalmology Times 2000; 25(0): 10-11.
- Fierz3 AB, Kaufman DI, Lee AG, Eggenberger ER, Friend KE. Cabergoline in Prolactinomas. Neuro-Ophthalmology, 22:37-46, 1999.
- Lee AG, Eggenberger ER, Kaufman DI, Manrique C. Optic Nerve Enhancements on Magnetic Resonance Imaging in Arteritic Ischemic Optic Neuropathy. Journal of Neuro-Ophthalmology, 19(4): 235-237, 1999.
Abstracts
- Zhu DC, Nogle S, Doyle S, Russell D, Covassin T, Pearson R, DeMarco JK, Kaufman D. Identify Potentially Vulnerable Functional Networks to Concussion in Sports: a Resting-State fMRI Longitudinal Study. Poster Presentation at the Big-Ten/CIC-Ivy League 2015 TBI Summit, July 16, 2015, Chicago, Illinois.
- Zhu DC, Covassin T, Nogle S, Doyle S, Russell D, Pearson R, DeMarco JK, Kaufman D. Identify Potentially Vulnerable Functional Networks to Concussion in Sports: a Resting-State fMRI Longitudinal Study. Multimedia e-poster presentation at the International Society of Magnetic Resonance in Medicine 23rd Annual Meeting, June 3, 2015, Ontario, Canada.
- Saeed A, Kaufman, DI. Acute Retinal Necrosis in the Setting of Varicella Zoster Vasculopathy - Case Report & Review of Literature. Poster Presentation at the American Academy of Neurology 67th Annual Meeting, April 22, 2015, Washington DC.
- Zhu DC, Covassin T, Nogle S, Doyle S, Russell D, Pearson R, Monroe J, Liszewski C, DeMarco JK, Kaufman D. The Dynamically Changing Default-Mode Network after Concussion in Sports: a Resting-State fMRI and DTI Integration Study. Oral presentation in International Society for Magnetic Resonance in Medicine, 22nd Annual Meeting and Exhibition, May 10-16, 2014, Milan, Italy.
- Zhu DC, Covassin T, Nogle S, Doyle S, Russell D, Pearson R, Monroe J, Liszewski C, DeMarco JK, Kaufman D. A Potential Biomarker in Sports-Related Concussion: Brain Functional Connectivity Alteration of the Default-Mode Network Measured with Sequential Resting-State fMRI. American Academy of Neurology Annual Meeting, April 26-May 3, 2014, Philadelphia, USA.
- Zhu DC, Pearson R, Monroe J, Nogle S, Doyle S, Russell D, Liszewski C, Aniskiewicz A, Shingles M, Dietzel D, Andary M, DeMarco JK, Kaufman D. The dynamically changing default-mode network functional connectivity after concussion in sports. International Society for Magnetic Resonance in Medicine, 21st Annual Meeting and Exhibition, April 20-26, 2013, Salt Lake City, Utah, USA.
- Young B, Eggenberger E, Kaufman D. Current electrophysiology in ophthalmology: a review. Current Opinion in Ophthalmology. 2012 Nov;23(6):497-505.
- Huang J, Cooper TG, Satana B, Kaufman DI, Cao, Y. Association Between Visual Distortion and activity in Migraine Patients. Proc. Intl. Soc. Mag. Reson. Med., Vol. 9, 2001, page 1319.
- Santos RN3, Eggenberger ER, Kaufman DI. The Intracranial Tuberculoma that was Thought to Be Neurosarcoidosis. North American Neuro-Ophthalmologic Society, Rancho Mirage, California, February 18-22, 2001, J Neuro-Ophthalmol, Vol. 21, No. 2, 2001.
- Newman N, Dickersin K, Kaufman DI, Kelman S, Scherer R. Characteristics of Patients with Nonarteritic Anterior Ischemic Optic Neuropathy Eligible for the Ischemic Optic Neuropathy Decompression Trial. Archives Ophthalmology. November, 1996. Vol.(114).
Book Chapters
- Glisson, CC and Kaufman, DI. How Do I Manage an Internuclear Ophthalmoplegia? In: Curbside Consultation in Neuro-Ophthalmology: 49 Clinical Questions. Lee, ed. 2015.
- Glisson, CC and Kaufman, DI. How Do I Manage an Internuclear Ophthalmoplegia? In: Curbside Consultation in Neuro-Ophthalmology: 49 Clinical Questions. Lee, ed. 2009.
- Kaufman DI. Peripheral Demyelinating and Axonal Disorders. In: Walsh and Hoyt’s Clinical Neuro-Ophthalmology Vol VI, Miller and Newman, eds, 2006.
- Kaufman DI and Eggenberger ER. Optic Nerve and Chiasm. In: Disorders of visual processing, Celesia G, ed. Elsevier Publisher, 2005.
- Kaufman DI. Ancillary Electrophysiologic Testing. In: Neuro-Ophthalmology The Practical Guide, Levin LA and Arnold AC eds., pp. 422-437, Thieme Medical Publishers, Inc. 2005.
- Kaufman, DI, Eggenberger ER, co-Editors. In: Ophthalmology Clinics of North America, September 2004. Elsevier Inc.
- Kaufman, DI. Acute Monosymptomatic Optic Neuritis: Potential Clues to Early Therapy in Multiple Sclerosis. In: Early Indicators, Early Treatments, Neuroprotection in Multiple Sclerosis, Hommes OR and Comi G, Eds., pp. 155-162, Springer-Verlag Italia, Milan, 2004.
- Kaufman, DI. Optic Nerve Disorders, Encyclopedia of the Neurological Sciences, (eds: Aminoff, M., and Daroff, R.) Vol. 3, pp. 686-690, Academic Press, San Diego, 2003.
- Kaufman D. Peripheral Demyelinating and Axonal Disorders. In: Miller NR and Newman NJ, eds., Walsh and Hoyt’s Clinical Neuro-Ophthalmology, fifth edition. Williams and Wilkins, 1998.
- Kaufman DI, Siebert JE, Pernicone JR, Eggenberger E. The Use of Magnetic Resonance Angiography in Neuro-Ophthalmology. In: Berman EL, Wirtschafter JD eds. Imaging, Ophthalmology Clinics of North America 7(3):487-508, 1994.
- Kaufman DI, Siebert JE, Pernicone JR: Magnetic Resonance Angiography Relevant to Neuro-Ophthalmology. In: Neuro-Ophthalmology Disorders, Tusa RJ and Newman SA, Eds., pp. 367-402, Marcel Dekker, Inc., NY, 1995.
Research Interests
Using the afferent visual system and electrophysiology to assess prognosis and early therapeutic strategies for brain disease such as multiple sclerosis and stroke.
Clinical neuro-visual disorders including optic neuritis, pseudotumor cerebri, ischemic optic neuropathy, ocular effects of tamoxifen, and Temporal Arteritis.
Awards
Michigan State University College of Osteopathic Medicine Faculty Achievement Award (2016), MSU AT&T Faculty-Staff Instructional Technology Team Award. NOP 552: Medical Neuroscience (2011), Clinical Science Faculty Award Michigan State University Class of 2009 (2011), Sparrow Health System’s “Physician of the Year” (2008), American Academy of Ophthalmology “Best Paper” – Neuro-Ophthalmology Free Paper Session, presented at the AAO (2007), American Osteopathic Association Presidential Citation for Excellence (2006)
Certifications
Board Certified, Neurology, American Board of Neurology and Psychiatry
Memberships
Fellow, American Neurological Association , American Academy of Neurology, American College of Neurology and Psychiatry, Walsh Society, North American Neuro-Opthalmology Society, American Osteopathic Association, Michigan Association of Osteopathic Physicians and Surgeons, American Osteopathic College of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, American Academy of Ophthalmology