Rishi Gupta, M.D.
Assistant Professor, Neurology
Division of Cerebrovascular Diseases
Director, Neuroendovascular Services

Academic Appointments

• 2006-present: Assistant Professor, Michigan State University, Neurology

Postdoctoral Training

• 2004-2006: Fellow, University of Pittsburgh, Neurointerventional Radiology
• 2003-2004: Fellow, The Cleveland Clinic Foundation, Vascular Neurology/Neurocritical Care
• 2000-2003: Resident: Columbia University, Neurology
• 1999-2000: Intern, University of Nevada, Internal Medicine

Education

• M.D., Meharry Medical College, 1999
• B.S., Bioengineering, Columbia University, 1995

Procedures Performed

• Coil embolization of cerebral aneurysms
• Acute stroke thrombolysis and mechanical thrombectomy
• Carotid artery stenting and angioplasty
• Intracranial atherosclerotic stenting and angioplasty
• Embolization of intra- and extracranial tumors pre-operatively
• Embolization for Epistaxis (Nosebleeds)
• Embolization of dural AV Fistulas and AVMs
• Spinal angiography and embolization of spinal AVM’s
• Treatment of carotid artery pseudoaneurysms
• Stenting of subclavian artery stenosis

Research Interests

Dr. Gupta is interested in the treatment of acute ischemic stroke through neuroendovascular techniques. He is currently looking at methods to select patients for acute stroke therapy beyond traditional time windows. Currently only 1-2% of patients in the United States are treated with intravenous t-PA for acute ischemic stroke due to a variety of reasons. By increasing the time window to treatment by utilization of physiology guided criterion a larger proportion of patients may benefit from various therapies. These time windows can also be potentially lengthened with use of neuroprotective agents that are initiated in the field by EMS. Through collaboration with his colleague Dr. Majid, the hope is to develop a multimodal approach to administering a neuroprotectant therapy quickly followed by a imaging the brain to assess its physiology and then reopen the occluded artery with the appropriate therapy.

Selected Publications

• Gupta R, Al-Ali F, Thomas AJ, Horowtiz MB, Barrow T, Vora NA, Uchino K, Hammer MD, Wechsler LR, Jovin TG. Safety, feasibility and short term follow-up of drug eluting stent placement in the intra- and extracranial circulation. Stroke. 2006; 37: 2562-2566.
• Gupta R, Yonas H, Gebel J, Goldstein S, Horowitz M, Wechsler LR, Hammer MD, Uchino K, Jovin TG. Reduced pre-treatment ipsilateral MCA cerebral blood flow is predictive of symptomatic hemorrhage post intra-arterial thrombolysis in acute ischemic stroke. Stroke. 2006; 37:2526-2530.
• Gupta R, Thomas A, Horowitz M. Intracranial head and neck tumors: endovascular considerations, present and future. In Press, Neurosurgery.
• Gupta R, Vora NA, Horowitz MB, Tayal AH, Hammer MD, Uchino K, Wechsler LR, Levy EI, Jovin TG. Multimodal reperfusion therapy for acute ischemic stroke: factors predicting vessel recanalization. Stroke. 2006; 37: 986-990.
• Jovin TG, Gupta R, Uchino K, Jungreis CA, Wechsler LR, Hammer MD, Tayal AH, Horowitz MB. Emergent stenting of extra-cranial internal carotid artery occlusion in acute stroke has a high revascularization rate. Stroke. 2005; 36:2426-2430.
• Gupta R, Abou-Chebl A, Bajzer CT, Schumacher HC, Yadav JS. Rate, predictors and consequences of hemodynamic disturbances after carotid artery stenting. Journal of Americal College of Cardiology. 2006; 47:1538-1543.
• Schumacher HC, Gupta R, Meyers PM. Advances in Revascularization for Acute Ischemic Stroke Treatment. Expert Rev Neurother. 2005; 5(2) 189-201.
• Gupta R, Jovin TG, Krieger DW. Therapeutic hypothermia for stroke: do new outfits change an old friend? Expert Rev Neurother. 2005; 5(2): 235-246.
• Gupta R, Connolly ES, Mayer SA, Elkind MSV. Hemicraniectomy for massive middle cerebral artery territory infarction: A systematic review. Stroke 2004;35:539-543.
• Tayal AH, Gupta R, Uchino K, Hammer MD, Jovin TG, Wechsler LR, Yonas H, Gebel JM. Quantitative Perihematomal Blood Flood in Spontaneous Intracerebral Hemorrhage Predicts Functional Outcomes. In press, Stroke.
• Jovin TG, Gupta R, Horowitz MB, Grahovac SZ, Jungreis CA, Wechsler LR, Gebel JM, Yonas H. Pre-treatment ipsilateral regional cortical blood flow influences vessel recanalization in intra-arterial thrombolysis for MCA occlusion. In press, AJNR Am J Neuroradiol.