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Faculty

Douglas Postels, M.D.
Associate Professor, Neurology

Academic Appointments
  • 8/2010 - present: Associate Professor, Michigan State University, Neurology & International Neurologic and Psychiatric Epidemiology Program
  • 1/2003 - 7/2010: Pediatric Neurologist and Lead Physician of Neurology Department, Presbyterian Medical Group, Albuquerque, New Mexico
  • 7/1996 - 12/2001: Head, Division of Pediatric Neurology- Ochsner Clinic, Pediatric Residency Program Co-Director (Tulane/Ochsner), New Orleans, Louisiana
  • 12/1993 – 6/1995: House Pediatrician, St. Luke’s Hospital, Chesterfield, Missouri

Postdoctoral Training

  • July 1995–June1996     State University of New York, Stony Brook, New York; Fellow in Pediatric Neurology
  • July 1991–Nov 1993    St. Louis Children’s Hospital, St. Louis, Missouri; Fellow in Pediatric Neurology
  • July 1988– June1991    Wilford Hall USAF Medical Center, San Antonio, Texas; Resident in Pediatrics

Education

  • Michigan State University; MS in Epedemiology - ongoing
  • Health Care Executive Program, University of New Orleans, Louisiana, 1999.
  • M.D., Loyola University Stritch School of Medicine, Maywood, Illinois, 1984-1988.
  • B.S., Degree in Microbiology Indiana University, Bloomington, Indiana, 1980-1984.

Honors and Awards

  • 2008: Visiting Professor Award, Child Neurology Society
  • 2007: World Federation of Neurology- clinical work and taught a one month rotation in pediatric neurology to residents and medical students at Queen Elizabeth Central Hospital in Blantyre, Malawi
  • 1997-Present: Board-Certified “Neurology with Special Qualifications in Child Neurology,” American Board of Psychiatry and Neurology
  • 1994: Board Certified in General Pediatrics, American Board of Pediatrics (not renewed)
  • 1989: Diplomate, National Board of Medical Examiners
  • 1988: Graduation cum laude, Loyola University Stritch School of Medicine
  • 1987: Alpha Omega Alpha, Loyola University Stritch School of Medicine

Clinical Interests

As a practicing pediatric neurologist, my clinical work is with disorders of the nervous system affecting children. Disorders I most commonly diagnose and treat include epilepsy, headache, movement disorders, developmental abnormalities, and disorders of metabolism affecting the nervous system. I have done extensive clinical work in the developing world and my research interests are in the epidemiology and clinical care of nervous system disorders of children in sub-Saharan Africa.

Selected Publications

  • Postels D, Chimalizeni Y, Mallewa M, et al. Cerebral Malaria; Scourge of African Children; Future Neurology 2013;8(1):67-85. Postels D, Birbeck G, Valim C, et al. Seasonal Differences in Retinopathy Negative versus Retinopathy Positive Cerebral Malaria; Am J Trop Med Hyg 2013;88(2):315-318.
  • Postels D, Taylor T, Molyneux M, et al. Neurologic Outcomes in Retinopathy Negative Cerebral Malaria Survivors. Neurology 2012;79(12)1268-1272.
  • Postels D and Birbeck G. Children with Retinopathy Negative Cerebral Malaria: A Pathophysiological Puzzle. Pediatric Infectious Disease Journal, Nov 2011; 30(11):953-956
  • Postels D and Birbeck G. Cerebral Malaria. In Handbook of Clinical Neurology, 3rd series. Garcia H, Tanowitz H, and Del Bruto O, eds. Elsevier Publishers (in press)
  • Van Loon G, Postels D, Heikens G. A seven year old Malawian Girl with severe pernicious anemia. Tropical Pediatrics 35 (2), 37-40.

Ad hoc reviewer: Lancet Neurology, Transactions for the Royal Society of Tropical Medicine, PLoS Medicine, Malaria Journal, Clinical Audit

Research

Ongoing Research Support:

  • World Federation of Neurology     Postels (PI)     06/01/11-05/31/13
    PeNETTS: Pediatric Neurologic Educational Training Tool and Site. Development of a website and CD-ROM based educational aid for health care workers caring for children with pediatric neurologic disease in the developing world.
  • Michigan State University Department of Neurology      08/01/10-Present
    Departmental internal support for research expenses, international travel, and pursuit of a Masters in Epidemiology.
  • National Institutes of Health     Birbeck (PI)     7/1/2012-6/30/2015
    A Dose-Escalation, Safety and Feasibility Study of Enteral Levetiracetam for Seizure Control in Pediatric Cerebral Malaria This is a Malawi based dose escalation, safety and feasibility study of enteral levetiracetam in pediatric cerebral malaria. This study will lay the groundwork for future efficacy studies aimed at improving seizure control and ultimately decreasing the neurologic morbidity in pediatric cerebral malaria. My role involves cEEG interpretation and working with the PI in subject clinical care.

Research Applications Pending Review

  • R03 PAR-11-262      Postels (PI)     4/1/2013-3/31/2015
    Viral co-infections in Retinopathy Negative Cerebral Malaria
    This is a study of archived serum and cerebral spinal fluid samples taken from children with retinopathy positive and retinopathy negative cerebral malaria and controls, to assess for the presence of acute viral co-infections. My role as PI is with study conception, data gathering, and interpretation.
  • R21 PAR-11-031     Postels and Idro (co-PI)     12/1/2013-11/30/2015
    Epilepsy or Developmental Disability from Uncomplicated Malaria
    This study develops screening and developmental assessment tools useful to assess African children as young as 6 months old for developmental disabilities or epilepsy. It assesses disability and epilepsy rates in young children living in eastern Uganda.
  • U01 (renewal) PAR-11-260     Taylor (PI)     07/1/2013 – 06/30/2018
    Mechanisms and Markers of Increased Brain Volume in Pediatric Cerebral Malaria
    The major goals of this project are to determine the underlying pathologic mechanisms contributing to increased intracranial pressure/ brain volume in children at highest risk of mortality from cerebral malaria.   Role: Investigator.

Background

Prior to joining the faculty of Michigan State University (MSU) in August, 2010, Dr. Postels’ was a practicing US- based clinical pediatric neurologist. His first work in sub-Saharan Africa was in 2007, when he spent time providing clinical care, but also was heavily involved in education of registrars and medical students in Blantyre, Malawi.

These ties will continue to be strengthened during his Ghanaian collaborators’ visits to Malawi, as well as working alongside them in Kumasi, Ghana.

 

   
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