Michigan State University Neurology and Ophthalmology

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Residents

Jiangyong Min (John Min), M.D., M.Sc.

Anticipated Residency Completion:

2012

Hometown:

China.

Graduate Education and Medical School:

M.D., Christian-Albrechts University School of Medicine, Kiel, Germany, 1998.

Post Graduate Education, Internship, and other training:

Research Fellow, Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 1999-2002.
Instructor, Beth Israel Deaconess Medical Center, Harvard Medical School, 2002-2007.
Research Assistant Professor, St. Elizabeth Medical Center, Tufts University School of Medicine, 2005-2007.
Intern, Michigan State University/Sparrow Health Systems, 2008-2009.
Resident, Michigan State University/Sparrow Health Systems Neurology Residency, 2009 - Present.

Fellowship interests/Special neurology interest:

Cerebrovascular disorders, Endovascular interventions, Vascular biology.

Research and Publications:

Min JY, Meissner A, Geldmacher H, Alexander H, El-Mokhtari NE, Simon R. Heterogeneity of noninvasive arrhythmic risk indications in patients with ischemic cardiomyopathy. J Electrocardiology 1998;31(3):221-226.
Meissner A, Min JY, Simon R. Effects of angiotensin II on inotropy and intracellular Ca2+ handling in normal and hypertrophied rat myocardium. J Mol Cell Cardiol 1998; 30:2507-2518.
Meissner A, Min JY, Haake N, Hirt S, Simon R. Dantrolene sodium improves the force-frequency relationship and ß-adrenergic responsiveness in failing human myocardium. Eur J Heart Failure 1999, 1:177-186
Sandmann S, Min JY, Meissner A, Simon R. Effects of the calcium channel antagonist mibefradil on haemodynamic parameters and myocardial Ca2+-handling in infarct-induced heart failure in rats. Cardiovasc Res 1999; 44: 67-80.
Min JY, Sandmann S, Meissner A, Unger T, Simon. Differential effects of mibefradil, verapamil, and amlodipine on myocardial function and intracellular Ca2+ handling in rats with chronic myocardial infarction. J Pharmacology and Experimental Therapeutics 1999; 291:1038-1044.
Min JY, Hampton TG, Wang JF, DeAngelis J, Morgan JP. Depressed tolerance of fluorocarbon-simulated ischemia in failing rat myocardium due to impaired intracellular Ca2+ modulation. Am J Physiol 2000; 278: H1446-H1456
Wang JF, Ren X, DeAngelis J, Min JY, Zhang Y, Hampton T, Amende I, Morgan JP. Differential patterns of cocaine-induced organ toxicity in murine heart versus liver. Exp Bio Med 2001; 226:52-60
Min JY, Ding B, Wang JF, Sullivan MF, Morgan JP. Metoprolol attenuates postischemic myocardial stunning by improving intracellular Ca2+ handling in normal and postinfarction rat myocardium. Eur J Pharmacol 2001, 422:115-25
Min JY. Long-term improvement of cardiac function by transplantation of embryonic stem cells in post-infarcted rats. Audio-tape. The American College of Cardiology Extended Learning. Vol. 33, No. 8 (August) 2001, USA
Min JY, Yang YK, Liu L, Morgan JP, Xiao YF. Transplantation of embryonic stem cells improves cardiac function in postinfarcted rat. J Appl Physiol, 2002, 92:288-296
Wang JF, Zhang J, Min JY, Sullivan MF, Crumpacker CS, Abelmann WH, Morgan JP. Cocaine enhances myocarditis induced by encephalomyocarditis virus in murine model. Am J Physiol 2002; 282:H956-H963
Wang JF, Yang Y, Sullivan MF, Min JY, Cai J, Zeldin DC, Xiao YF, Morgan JP. Induction of cardiac Cytochrome P450 in cocaine-treated mice. Exp Biol Med 2002; 227(3):182-188
Wang JF, Sullivan MF, Min JY, Morgan JP. Cardiac toxicity of cocaine: from myocardial depression to cardiomyopathy. Cardiovascular Remodeling & Failure. Singal P.K., Dixon I.M.C., Kirshenbaum L.A., and Dhalla N.S. Kluwer Academic Publishers, Boston, MA, USA 2002.
Min JY, Meissner A, Wang J, Morgan JP. Mibefradil improves b-adrenergic responsiveness and intracellular Ca2+ handling in hypertrophied rat myocardium. Ex Biol Med, 2002, 227:336-344
Min JY, Liao H, Wang JF, Sullivan MF, Morgan JP. Genistein attenuates postischemic depressed myocardial function by increase myofilament Ca2+ sensitivity in rat myocardium. Exp Biol Med, 2002; 227(8): 632-638
Min JY, Sullivan MF, Wang JF, Amende I, Morgan JP, Hampton T. Increased Na+/Ca2+ exchanger expression attenuates myocardial dysfunction after myocardial infarction. Ann N Y Acad Sci 2002; 976: 480-482
Yang Y, Min JY, Sullivan MF, Chen Y, Morgan JP, Xiao YF. VEGF enhances functional improvement of infarcted hearts by transplantation of early-differentiated cells from ESCs. J Appl Physiol 2002; 93: 1140-1151.
Min JY, Sullivan MF, Xianhua Yan, Xin Feng, Hampton TG, Wang JF, Chu V, Amende I, Philipson KD, Morgan JP. Attenuation of postinfarcted myocardial dysfunction in transgenic mice with overexpression of Na+/Ca2+ exchanger. American Journal of Physiology (Heart Circ Physiol) 2002; 283: H2466-H2471
Wang JF, Yan X, Min JY, Sullivan MF, Hampton TG, Morgan JP. Cocaine downregulates cardiac SERCA2a and depresses myocardial function in the murine model. Can J Physiol Pharmacol 2002; 80(10): 1015-1021.
Min JY, Sullivan MF, Yang Y, Zhang JP, Converso KL, Morgan JP, Xiao YF. Significant Improvement of heart function by co-transplantation of human mesenchymal stem cells and fetal cardiomyocytes in postinfarcted pigs. Annual Thoracic Surgery 2002; 74: 1568-1575
Wang JF, Yang Y, Wang G, Min JY, Sullivan MF, Ping P, Xiao YF, Morgan JP. Embryonic stem cells attenuate viral myocarditis in murine model. Cell Transplant 2002; 11(8): 753-8
Wang JF, Sullivan MF, Min JY, Morgan JP. Cardiac toxicity of cocaine: from myocardial depression to cardiomyopathy. Cardiovascular Remodeling & Failure. Singal P.K., Dixon I.M.C., Kirshenbaum L.A., and Dhalla N.S. Kluwer Academic Publishers, Boston, MA, USA 2002.
Maynard S, Min JY, Merchan J, Lim KH, Li J, Mondal S, Libermann T, Morgan JP, Sellke FW, Epstein FH, Sukhatme V, Karumanchi SA. Excess placental sFlt-1 causes endothelial dysfunction, hypertension and proteinuria of pre-eclampsia. J Clin Invest 2003; 111(5): 649-658
Min JY, Yang Y, Sullivan MF, Ke Q, Converso KL, Morgan JP, Xiao YF. Long-term improvement of cardiac function by transplantation of embryonic stem cells in postinfarcted rats. J Thoracic Cardiovascular Surgery, 2003; 125(2): 361-369
Min JY, Meissner A, Feng X, Wang J, Malek S, Wang JF, Simon R, Morgan JP. Dantrolene: effects on abnormal intracellular Ca2+ handling and inotropy in postinfarcted rat myocardium. Eur J Pharmacol 2003; 471: 41-47
Xiao YF, Min JY, Morgan JP. Immunosuppression and xenotransplantation of cells for cardiac repair. Annual Thoracic Surgery, 2004; 77: 737-744
Himes N, Min JY, Lee R, Brown C, Shea J, Huang X, Xiao YF, Morgan JP, Burstein D, Oettgen P. In vivo magnetic resonace images of embryonic stems in a mouse model of myocardial infarction. Magnetic Resonance in Medicine 2004; 52:1214-1219
Xiao YF, Min JY, Morgan JP. Transplantation of embryonic stem cells for myocardial regeneration and angiogenesis. In Laham and Baim. Angiogenesis and direct myocardial revascularization. Human Press. NJ, USA. 2005.
Chen Y, Ke Q, Xiao YF, Wu G, Kaplan E, Hampton TG, Malek S, Min JY, Amende I, Morgan JP. Cocaine and Catecholamines Enhance inflammatory cell retention in the coronary circulation of mice by up-regulation of adhesion molecules. Am J Physiol (Heart Circ Physiol). 2005;288(5):H2323-2331.
Min JY, Chen Y, Malek S, Meissner A, Xiang M, Ke Q, Feng X, Nakayama M, Kaplan E, Morgan JP. Stem cell therapy in the aging hearts of Fischer 344 rats: Synergistic effects on myogenesis and angiogenesis. J Thoracic Cardiovascular Surgery; 2005; 130: 547-553.
Xiao YF, Min JY, Morgan JP. Transplantation of Embryonic Stem Cells for Myocardial Regeneration and Angiogenesis. In Laham and Baim. Angiogenesis and direct myocardial revascularization. Human Press. NJ, USA. 2005.
Malek S, Kaplan E, Wang JF, Ke Q, Rana JA, Chen Y, Rahim BG, Li M, Huang Q, Xiao YF, Verheugt FWA, Morgan JP, Min JY. Successful Implantation of Intravenously Administered Stem Cells Correlates with Severity of Inflammation in Murine Myocarditis. Pflugers Archiv-European Journal of Physiology 2006; 452(3):268-75.
Min JY, Huang X, Xiang M, Meissner A, Chen Y, Ke Q Kaplan E, Rana JR, Oettgen P, Morgan JP. Homing of intravenously infused embryonic stem cell-derived cells to injured hearts after myocardial infarction. J Thoracic Cardiovascular Surgery 2006; 131(4):889-97.
Toth A, Jeffers JR, Nickson P, Min JY, Morgan JP, Erhardt P. Targeted Deletion of Puma Attenuates Cardiomyocyte Death and Improves Cardiac Function during Ischemia/reperfusion. American Journal of Physiology , 2006 Jul;291(1):H52-60.
Chen Y, Amende I, Hampton TG, Yang Y, ke Q, Min JY, Xiao YF, Morgan JP. Vascular endothelial growth factor promotes cardiomyocyte differentiation of embryonic stem cells. Am J Physiol (Heart Circ Physiol) 2006 Oct; 291(4):H1653-8.
Xiang M, Wang J, Kaplan E, Oettgen P, Lipsitz L, Morgan JP, Min JY. Anti-apoptotic effect of implanted embryonic stem cell-derived early-differentiated cells in aging rats after myocardial infarction. J Gerontology: Biomedical Science. 2006 Dec;61(12):1219-1227.
Min J, Senut MC, Rajanikant K, Greenberg E, Bandagi R, Zemke D, Mousa A, Kassab M, Farooq MU, Majid A. Differential neuroprotective effects of carnosine, anserine, and n-acetyl carnosine against permanent focal ischemia. Journal of Neuroscience Research, in press, 2008.

Why did you choose to become part of Michigan State University Neurology?

Excellent academic and community atmosphere. Strongly encourage residents to take part in translational neuroscience research. Very friendly and helpful house staff and attendings.

If you were not a doctor, what would you have chosen as a career?

Teacher.

Extracurricular interests and activities:

Sports (swimming, bicycling, long-distance run), Music (classical and pop), Movies (romantic and adventure).